President Donald Trump on Monday demanded that Israel and Iran “immediately stop shooting” as the two adversaries exchanged fresh strikes overnight, threatening to derail U.S.-backed efforts to end the conflict.

Trump’s call came after Israel said it struck military targets and a petrochemical facility in southwestern Iran in retaliation for a barrage of Iranian missiles fired Sunday.

“Israel and Iran must immediately stop shooting,” Trump wrote on Truth Social.

The latest escalation marked the first reported Israeli strike on an Iranian energy facility since an April ceasefire temporarily halted direct hostilities between the two countries.

In a subsequent post, Trump said Israel and Iran are looking to reach a ceasefire.

“Both sides, Israel and Iran, are looking to do an immediate CEASEFIRE! Final negotiations on ‘Peace’ are proceeding, subject to ignorance or stupidity getting in its way. The Blockade will remain in place, and in full force and effect, until a ‘Final Deal’ is reached. Things should move quickly,” Trump said in the Truth Social post.

Despite the renewed violence, Trump insisted peace negotiations with Tehran remain on track and said Israeli Prime Minister Benjamin Netanyahu would not dictate the course of U.S. diplomacy.

“It’s not going to have any impact on the deal,” Trump told the Financial Times. “I call the shots. I call all the shots. He doesn’t call the shots.”

According to reports, Trump urged Netanyahu during a phone call Sunday to avoid additional military action because the administration believes a broader agreement with Iran remains within reach.

Hours after the call, Israel said it conducted new strikes against Iranian military targets. Iran’s Revolutionary Guards responded by launching missiles at Israel, while Israeli officials said air-defense systems intercepted incoming threats.

Israeli Ambassador Yechiel Leiter said Iran fired 11 ballistic missiles at Israel and vowed the Jewish state would continue targeting missile launch sites and military infrastructure.

The conflict widened further when the Israeli military said it intercepted a missile launched from Yemen, in what would be the first Houthi attack on Israel since the ceasefire.

U.S. Ambassador to Israel Mike Huckabee reported missile alerts sounding in Jerusalem early Monday, blaming Tehran for the attacks.

The renewed fighting pushed global oil prices sharply higher, with Brent crude rising more than 3% and climbing back above $96 per barrel.

Trump has repeatedly argued that Washington is close to securing a deal that would end the conflict while preventing Iran from obtaining a nuclear weapon. He has also pressed Israel to avoid actions he believes could jeopardize negotiations.

“We’re very close to a deal,” Trump said during a weekend interview. “Or I’m going to blow the hell out of them.”

The latest exchange of strikes underscores the fragile state of the ceasefire and the challenge facing the Trump administration as it seeks to broker a broader settlement in the region.