Joe Biden has rowed back on his optimism that a ceasefire would happen by Monday.
The president said reports of Israeli fire on Palestinians crowding around aid trucks would complicate talks.
He had previously hoped a deal could be struck between Israel and Hamas by the end of the weekend.
He added that a temporary ceasefire probably will not now happen by Monday.
Talks had been taking place in Cairo and Paris, with mediators Qatar, Egypt and the US in attendance.
A six-week pause in fighting was proposed, including an exchange of hostages for Palestinian prisoners.
Two dead in West Bank shooting
Two men have been killed in a shooting attack in the Israeli-occupied West Bank, Israeli emergency services say.
The Israeli military said a gunman opened fire at a gas station and was “neutralised” by security forces.
Pentagon chief: More than 25,000 women and children killed in Gaza
Reuters news agency has reported that during a congressional hearing, US defence secretary Lloyd Austin was asked how many Palestinian women and children had been killed by Israel since 7 October.
“It is over 25,000,” the Pentagon chief replied.
He said Israel can and should do more to protect civilians.
Approximately 21,000 precision guided munitions had been provided to Israel since the start of its war in Gaza, he added.
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